Metabolic stress and their nutrition therapy

Tarnopolsky describes a year-old triathlete who came in for a lipid study, but was found to have a mitochondrial disease slides The fact that this young man could competitively complete triathlons intrigued his team. A commitment to lifelong exercise compensated for his disease and allowed him to compete at high levels. Creatine and CoQ10 proved to be protective for his cells and increased his performance.

Metabolic stress and their nutrition therapy

I cannot tell you how many emails I get from people fretting over their ketone levels. At least, not to my satisfaction. And that is and always has been my goal in writing my blog: I explain things the way I would want someone to explain them to me, if I were new to all this.

And since no one—as far as I know, anyway—has tackled this subject the way I would, I finally had to just sit down and write this. There are few issues more controversial regarding ketogenic diets than whether you should measure your ketones.

There are valid reasons to measure, but there are also a lot—a lot—of misconceptions about measuring ketones and how to interpret the data. I will also be covering the difference between being fat adapted versus in ketosis.

I tried to do it in a few posts awhile back, but I think I the way I explain it here is much better because I will show you the biochemical pathways involved so you will be able to see how it actually works.

NOW I get it! Who Should Measure and Why The first thing to ask yourself is why you are measuring. Some of these conditions might be positively impacted only when ketone levels reach a certain threshold, while others might respond favorably to a general reduction in dietary carbohydrate load and inflammatory foods with no particular emphasis on staying in ketosis and no requirement to do so.

You might discover that you need to stay above a certain level in order to notice improvement, and you might be able to identify particular foods or activities e.

Ketones are the result, not the cause, of breaking down fat. The knowledgeable people in the KetoGains community have a saying for fat loss: These conditions are driven primarily by chronic hyperinsulinemiaso the main thing that helps them is lowering insulin.

Once more, for effect: If you feel especially great at a particular moment, you can test to see if maybe your ketones are a bit higher than usual, and this would tell you that you, personally, feel your best when your ketones are on the high end of normal.

For a while, anyway. Things change over time. The second thing to keep in mind: What matters is how you feel or whether your health condition is improving, not your ketone level.

Some people—usually young, athletic males—can generate a relatively large amount of ketones even while consuming more carbohydrate than would be considered a ketogenic diet level.

And a third thing: Several things can affect ketone levels fairly quickly.

Tuit Nutrition: Ketogenesis, Measuring Ketones, and Burning Fat vs Being in Ketosis

For example, eating a fat-rich meal—especially if it contains MCT oil or coconut oil—can elevate ketones in short order. Some people find that exercise raises ketones, and for many people, fasting will raise them too.

How to Interpret Ketone Measurements Measuring ketone levels can give you information about how your diet, sleep, stress levels, and exercise affect you.

You are literally peeing them out.

Metabolic stress and their nutrition therapy

So rather than being disappointed, you could take this as a good sign. That being said, urine test strips do serve a purpose. Seeing that little square turn pink or purple can be a big morale boost and serve as encouragement to stick with this way of eating. So it can be a positive reinforcement before anything else starts to change.

For interpreting blood ketones, there are a couple of pitfalls. Ketones are a fuel—just like glucose and fats.

Metabolic stress and their nutrition therapy

The level of ketones measured in the blood reflects the dynamic between ketone production and ketone utilization. So the glucose just lingers in the blood. But for some reason, when it comes to ketones, we automatically think that a buildup in the blood is a good thing.

Again, I fully recognize that there are medical conditions that might require a certain sustained level of blood ketones. We have come to the most important part of this post. The body runs on three primary fuels, but we can measure only two of them ourselves.

There are meters to measure glucose and ketones, but there are no fatty acid meters—at least, not yet.If you are a female that stores fat primarily in your belly, an apple instead of a pear, then this blog is for you.

And if you are not the type that likes all the science, then skip to the bottom and just read the “action steps” section.

🙂 The other day in the clinic [ ]. Basal metabolic rate (BMR) is the rate of energy expenditure per unit time by endothermic animals at rest.

It is reported in energy units per unit time ranging from watt (joule/second) to ml O 2 /min or joule per hour per kg body mass J/(h·kg).

Proper measurement requires a strict set of criteria be met. Clinical Guidelines. Authored by a talented group of GI experts, the College is devoted to the development of new ACG guidelines on gastrointestinal and liver diseases.

Join us on Friday, Dec. 2 at noon EST/9 a.m. PST as Mark Tarnopolsky MD, PhD, FRCP(C) discusses exercise and nutrition therapy for mitochondrial What to expect. Curriculum The NTC course is divided into 16 comprehensive modules that cover a full range of topics from the evolution of the modern diet, to anatomy and physiology, therapeutic nutrition strategies, and lifestyle support factors like movement, sleep, stress management, and community.

Metabolism involves a vast array of chemical reactions, but most fall under a few basic types of reactions that involve the transfer of functional groups of atoms and their bonds within molecules.

This common chemistry allows cells to use a small set of metabolic intermediates to carry chemical groups between different reactions. These group .

Tuit Nutrition: Ketogenesis, Measuring Ketones, and Burning Fat vs Being in Ketosis